Isotopically Labeled Compounds
Sigma Aldrich Fine Chemicals Biosciences L Glutamine 15N2 98 atom250MG
L Glutamine 15N2 98 atom250MG
Medchemexpress LLC 5Z,8Z,11Z,14Z-Eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid | 2692624-11-4 | 98.0% | 315.53 | 50 MG
Arachidonic acid-d11 is the deuterium labeled Arachidonic acid. It is an essential fatty acid and a major constituent of biomembranes. This product is provided as a colorless to light yellow liquid solution.
- Deuterium labeled
- Essential fatty acid
- Major constituent of biomembranes
- Colorless to light yellow liquid
- Purity of 98.0%
- Store at -20°C for up to 2 years
Medchemexpress LLC Ciprofloxacin-d8 (hydrochloride) | 1216659-54-9 | 98.8% | 2.5 MG
Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Pregnenolone-d4 | 145-13-1 | 1 MG
Pregnenolone-d4 is the deuterium-labeled version of Pregnenolone, a powerful neurosteroid and a primary precursor to various steroid hormones, including steroid ketones. It functions as a signaling-specific inhibitor of the cannabinoid CB1 receptor, thereby inhibiting the effects of tetrahydrocannabinol (THC) that are mediated by these receptors. Additionally, Pregnenolone can safeguard the brain from cannabis intoxication. It also acts as an activator for the TRPM3 channel and can weakly activate TRPM1 channels.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for potential impact on pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Adenine-13C | 86967-48-8 | 99.1% | 50 MG
Adenine-13C is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases found in the nucleic acid of DNA. It serves as a chemical component of both DNA and RNA. Adenine also plays a significant role in biochemistry, specifically in cellular respiration, forming both ATP and cofactors like NAD and FAD, and in protein synthesis.
- Isotope labeled for use as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
Medchemexpress LLC Metronidazole-13C2,15N2 | 1173020-03-5 | MFCD16652531 | 99.3% | 1 MG
Metronidazole-13C2,15N2 is the 13C-labeled and 15N-labeled version of Metronidazole. Metronidazole is a nitroimidazole antibiotic medication that is primarily used for anaerobic bacteria and protozoa. This compound is intended for research use only.
- Stable isotope-labeled compound
- Can be utilized as a tracer in research
- Serves as an internal standard for quantitative analysis
- Potential for pharmacokinetic and metabolic studies
Medchemexpress LLC Memantine-d6 (hydrochloride) | 1189713-18-5 | 99.8% | 1 MG
Memantine-d6 (hydrochloride) is a deuterium-labeled Memantine hydrochloride. It functions as a moderate affinity, uncompetitive NMDA receptor antagonist and inhibits CYP2B6 and CYP2D6. This compound is frequently used in research as a stable isotope-labeled standard and as a tracer for quantitative analysis.
- Deuterium labeled
- Moderate affinity, uncompetitive NMDA receptor antagonist
- Inhibits CYP2B6 and CYP2D6
- Stable isotope-labeled standard
- Suitable as a tracer
- Applicable for quantitative analysis (NMR, GC-MS, LC-MS)
Medchemexpress LLC Diclazuril-d4 | 1632495-80-7 | 97.8% | 1 MG
Diclazuril-d4 is a deuterium labeled Diclazuril, a potent and orally active anticoccidial agent. It is used in the research of infectious and parasitic diseases like coccidiosis, acute toxoplasmosis, and equine protozoal pyoencephalitis (EPM). It can also serve as a tracer and internal standard for quantitative analysis.
- Deuterium labeled form of Diclazuril
- Potent and orally active anticoccidial agent
- Tracer and internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Molecular weight: 411.66
- Formula: C17H5D4Cl3N4O2
- Appearance: Solid, white to yellow
- Purity: 97.8%
Medchemexpress LLC Ramipril-d5 (HOE-498-d5) | 1132661-86-9 | 99.0% | 1 MG
Ramipril-d5 is a deuterium-labeled form of Ramipril, a potent angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5 nM. It is specifically designed for research applications, serving as a reliable tracer and internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes like deuterium plays a crucial role in drug development, particularly for accurate quantitation, and can influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled form of Ramipril
- Potent ACE inhibitor with IC50 of 5 nM
- Suitable for research applications
- Functions as a tracer and internal standard
- Compatible with quantitative analysis methods (NMR, GC-MS, LC-MS)
- Supports drug development by aiding in quantitation
- May influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC L-Ascorbic-2-13C acid | 178101-89-8 | >99.9% | 1 MG
L-Ascorbic acid-13C-1 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. It selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM and is also a collagen. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Triptolide-d3 | 38748-32-2 | 91.98% | 363.42 | 1 MG
Triptolide-d3 is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root of *Tripterium wilfordii* with immunosuppressive, anti-inflammatory, antiproliferative, and antitumour effects. Triptolide is an NF-κB activation inhibitor. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences Formaldehyde-13C solution 20 wt. % in H2O, 99 atom % 13C | 3228-27-1 | MFCD00144372 | 1G
Formaldehyde-13C solution 20 wt. % in H2O, 99 atom % 13C | Mol Wt: 31.02 | 3228-27-1 | MFCD00144372 | 1G
Medchemexpress LLC rel-Sertraline-d3 hydrochloride | 1330180-66-9 | 99.5% | 1 MG
rel-Sertraline-d3 hydrochloride is a deuterium-labeled form of Sertraline hydrochloride, an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is utilized in research for various diseases, including major depressive disorder. This compound serves as a tracer or an internal standard for quantitative analysis. Its molecular weight is 345.71 and its formula is C17H15D3Cl3N. It appears as a solid and ships at room temperature within the continental US.
- Deuterium-labeled Sertraline hydrochloride
- Antidepressant of the selective serotonin reuptake inhibitor (SSRI) class
- Used as a tracer or internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Molecular weight of 345.71
- Chemical formula C17H15D3Cl3N
- Long-term powder storage at -20°C for 3 years
- Solution storage at -80°C for 6 months or -20°C for 1 month
Cayman Chemical Enobosarm-d4 500ug
An internal standard for the quantification of enobosarm by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Ubiquitin 15N human 98 ato5MG
Ubiquitin 15N human 98 ato5MG